Saline Laxatives Market Analysis Report, Regional Outlook with Key Players – Beutlich Pharmaceuticals, Bayer AG, C.B. Fleet Company, Salix Pharmaceuticals, Safeway, and Supervalu

Saline laxatives are used to treat constipation or to cleanse the colon in preparation for a colonoscopy. Saline laxative work by absorbing water into the intestine, which softens the stool. These drugs rapidly increase the frequency of complete bowel actions, reduce constipation-associated symptoms and improve disease-related quality of life. Mild saline laxatives such as milk of magnesia and oral magnesium hydroxide have been used to treat constipation during pregnancy.

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Saline laxatives are soluble inorganic salts that contain multivalent cations or anions. Examples of saline laxatives include citrate salts (Royvac), magnesium preparations (Phillips’ Milk of Magnesia), sulfate salts, and sodium phosphate. A saline laxative is categorized as a hyperosmotic drug, which works by pulling excess water into the bowels from tissues. This action softens the stools and leads to bowel movements. Saline laxatives can be combined with other types of laxatives in a combination medication.
The choice of saline laxative (magnesium sulfate, magnesium hydroxide, magnesium citrate, sodium sulfate, sodium phosphate) is random. For instance, in patients with either cardiac or renal dysfunction, excessive absorption of phosphorus, sodium, or magnesium can lead to electrolyte and volume overload and over use of laxative can cause dehydration.

Market Dynamics

Increasing number of constipation incidences coupled with rising geriatric population base worldwide is the major factor driving the saline laxatives market growth. Low fluid and fibre diet intake may also play a major role in onset of constipation. According to the AGA Journal 2011 data, constipation affects 12% to 19% of Americans every year; its prevalence increases with age and it affects women more than men. Constipation causes psychological impairment, social distress, sexual dysfunction, altered interpersonal relationship, and impairment in quality of life. It has a major impact on social and economic burden. As per U.S. FDA, Americans spend more than US$ 700 million annually on over-the-counter laxatives.

Constipation during pregnancy is a common problem. According to the BMC journal 2012 data, the reported prevalence of constipation in pregnant women varies between 11 to 38% and occurs mostly during the third trimester, although symptoms can be present from 12 weeks gestation. However, most obstetricians advise avoiding laxatives during pregnancy and prescribe stool softeners instead due to its potential side effects. Increasing prevalence of constipation coupled with sedentary lifestyle, consumption of low fluid and fiber diet and rising geriatric population are major factors expected to drive the global saline laxative market growth.

Side effects associated with over dose of saline laxative including cathartic colon, intestinal paralysis, lazy or laxative gut, pancreatitis, irritable bowel syndrome can confine the saline laxative market growth during the forecast period. In 2014, the FDA issued a warning about the use of saline laxatives. Saline laxatives that contain the active ingredient sodium phosphate can lead to abnormal levels of electrolytes, dehydration, heart and kidney problems, and death.

Global Saline Laxatives Market, By Age Group:

Pediatric
Adult

Global Saline Laxatives Market, By Route of Administration:

Oral
Rectal

Global Saline Laxatives Market, By Distribution Channel:

Hospital Pharmacy
Retail Pharmacy
Online Pharmacy

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North America saline laxative market is expected to foresee increase in revenue share, owing to increasing constipation related emergency in regional hospitals. For instance, according to a study published in a journal in 2015, national cost of constipation-related emergency department visits in the U.S. increased by 121.4% from 723,886,977 in 2006 to 1.6 billion in 2011.

Europe saline laxative market is anticipated to grow at significant rate, owing to increasing spending over the use of laxatives.

What Information does this report contain?

-Historical data coverage: 2013 to 2017; Growth Projections: 2018 to 2026.
-Expert analysis: industry, governing, innovation and technological trends; factors impacting development; drawbacks, SWOT.
-6-7 year performance forecasts: major segments covering applications, top products and geographies.
-Competitive landscape reporting: market leaders and important players, competencies and capacities of these companies in terms of production as well as sustainability and prospects.

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